Desc: La Grippe espagnole, la grande tueuse: Directed by Paul Le Grouyer. With Éric Caravaca, David Lloyd George, Charles Chaplin, Woodrow Wilson. In April 1918, a disease of unknown origin swept across the five continents. In 18 months, millions of lives that had not been taken by the war were swept away by a virus that would cause the worst pandemic in history: the Spanish flu.